BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE
Post-LOEbenazepril hydrochloride and hydrochlorothiazide
ANDAORALTABLET
Approved
Feb 2004
Lifecycle
Post-LOE
Competitive Pressure
30/100
Mechanism of Action
Mechanism of Action Benazepril and benazeprilat inhibit angiotensin-converting enzyme (ACE) in human subjects and in animals. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. Angiotensin II also stimulates aldosterone…
Pharmacologic Class:
Thiazide Diuretic