BECONASE AQ by GSK is clinical pharmacology mechanism of action following topical administration, beclomethasone dipropionate produces anti-inflammatory and vasoconstrictor effects. Approved for recurrence of nasal polyps following surgical removal. First approved in 1987.
Drug data last refreshed 16h ago · AI intelligence enriched 2w ago
BECONASE AQ is an intranasal metered spray formulation of beclomethasone dipropionate, a topical corticosteroid indicated for recurrence of nasal polyps following surgical removal. It works by producing anti-inflammatory and vasoconstrictor effects through hydrolysis to its active metabolite beclomethasone-17-monopropionate (B-17-MP), which suppresses multiple inflammatory cell types and mediators.
Product approaching end-of-life with minimal current revenue ($1M spending, 3,065 claims in 2023); limited team growth expected.
CLINICAL PHARMACOLOGY Mechanism of Action Following topical administration, beclomethasone dipropionate produces anti-inflammatory and vasoconstrictor effects. The mechanisms responsible for the anti-inflammatory action of beclomethasone dipropionate are unknown. Corticosteroids have been shown to…
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