BECONASE
LOE ApproachingNDANASALAEROSOL, METERED
Approved
Sep 1981
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
BECONASE by GSK is clinical pharmacology mechanism of action following topical administration, beclomethasone dipropionate produces anti-inflammatory and vasoconstrictor effects. Approved for recurrence of nasal polyps following surgical removal. First approved in 1981.
Drug data last refreshed 20h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
BECONASE is beclomethasone dipropionate, a topical intranasal corticosteroid aerosol approved for prevention of nasal polyp recurrence following surgical removal. It works via rapid esterase-mediated conversion to its active metabolite (B-17-MP), which suppresses inflammatory cell activity and mediators in nasal mucosa. The drug produces localized anti-inflammatory and vasoconstrictor effects with minimal systemic absorption when used intranasally.
LOE Approaching
Product is approaching loss of exclusivity with limited current market activity; career roles likely focused on transition planning and cost management rather than growth initiatives.
Mechanism of Action
CLINICAL PHARMACOLOGY Mechanism of Action Following topical administration, beclomethasone dipropionate produces anti-inflammatory and vasoconstrictor effects. The mechanisms responsible for the anti-inflammatory action of beclomethasone dipropionate are unknown. Corticosteroids have been shown to…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.