BARHEMSYS (amisulpride) by Acacia Pharma is dopamine d2 antagonists [moa]. Approved for schizophrenia, postoperative nausea and vomiting. First approved in 2020.
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BARHEMSYS (amisulpride) is an intravenous dopamine D2 receptor antagonist approved in 2020 for schizophrenia and postoperative nausea and vomiting (PONV). It works by blocking dopamine signaling in the central nervous system to reduce psychotic symptoms and nausea. The IV route provides rapid onset, making it particularly valuable in acute care settings.
At peak lifecycle with strong patent protection through 2038, BARHEMSYS is in active commercialization phase; career opportunities exist in sales, medical affairs, and brand management roles.
Dopamine D2 Antagonists
Dopamine-2 Receptor Antagonist
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The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.
Study of Intravenous Amisulpride for Prophylaxis of Post-operative Nausea and Vomiting (PONV) in Pediatric Patients
An Open-Label, Single-Arm Clinical Trial Evaluating the Safety and Efficacy of Amisulpride in Treating Patients With Schizophrenia and Schizoaffective Disorder Who Have Treatment-Resistant Positive Symptoms
A Comparison of the Efficacy of Amisulpride and Placebo in the Prevention of PONV in Patients at Moderate-to-high Risk of PONV.
Post Operative Nausea and Vomiting (PONV) Rescue Outcomes After Amisulpride Treatment
Effects of a Single Dose of Amisulpride on Functional Brain Changes
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Upgrade to Pro — $25/moBARHEMSYS offers stable, peak-lifecycle career opportunities with strong commercial infrastructure and long patent protection, though limited clinical pipeline means advancement is primarily commercial-track. Career growth will focus on market penetration, managed care, and competitive positioning against entrenched antipsychotic and antiemetic therapies.