NDAORALTABLET
Approved
Aug 1992
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
6
Data completeness
4/8 — Partial
BANAN (cefpodoxime proxetil) by Daiichi Sankyo is clinical pharmacology absorption and excretion: cefpodoxime proxetil is a prodrug that is absorbed from the gastrointestinal tract and de-esterified to its active metabolite, cefpodoxime. Approved for development of drug-resistant bacteria, maintain the effectiveness of cefpodoxime proxetil, other antibacterial drugs and 3 more indications. First approved in 1992.
Drug data last refreshed Yesterday · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
BANAN (cefpodoxime proxetil) is an oral third-generation cephalosporin antibiotic approved in 1992 for treating bacterial infections caused by susceptible pathogens. It is a prodrug absorbed from the GI tract and de-esterified to its active metabolite cefpodoxime, which inhibits bacterial cell wall synthesis. The drug achieves adequate tissue penetration, including in skin, tonsillar, and other tissues, with 50% bioavailability and minimal hepatic metabolism.
LOE Approaching
Product approaching loss of exclusivity with minimal recent spending data, suggesting reduced commercial investment and smaller brand support teams.
Mechanism of Action
CLINICAL PHARMACOLOGY Absorption and Excretion: Cefpodoxime proxetil is a prodrug that is absorbed from the gastrointestinal tract and de-esterified to its active metabolite, cefpodoxime. Following oral administration of 100 mg of cefpodoxime proxetil to fasting subjects, approximately 50% of the…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.