BACTROBAN
LOE ApproachingNDATOPICALCREAM
Approved
Dec 1997
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
3/8 — Basic
BACTROBAN by GSK is clinical pharmacology pharmacokinetics following single or repeated intranasal applications of 0. First approved in 1997.
Drug data last refreshed 20h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
BACTROBAN is a topical antibiotic cream containing mupirocin that inhibits bacterial protein synthesis by binding to isoleucyl transfer-RNA synthetase. It treats impetigo, staphylococcal infections, and traumatic skin lesions, with established clinical utility for nasal eradication of methicillin-resistant S. aureus (MRSA) colonization as part of institutional outbreak control programs. The drug demonstrates minimal systemic absorption when applied topically to intact skin in adults.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30% index), suggesting declining team size and shift toward cost/supply optimization roles.
Mechanism of Action
CLINICAL PHARMACOLOGY Pharmacokinetics Following single or repeated intranasal applications of 0.2 gram of BACTROBAN NASAL 3 times daily for 3 days to 5 healthy adult male subjects, no evidence of systemic absorption of mupirocin was demonstrated. The dosage regimen used in this study was for…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.