AZELEX

LOE Approaching

azelaic acid

NDATOPICALCREAM
Approved
Sep 1995
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
11

Mechanism of Action

CLINICAL PHARMACOLOGY The exact mechanism of action of azelaic acid is not known. The following in vitro data are available, but their clinical significance is unknown. Azelaic acid has been shown to possess antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis. The…

Clinical Trials (5)

NCT03418610Phase 4Completed

Azelaic Acid Foam 15% in the Treatment of Papulopustular Rosacea

Started Dec 2017
5 enrolled
Rosacea, Papulopustular
NCT02058628Phase 4Completed

Comparison of the Efficacy and Safety of Clindamycin + Benzoyl Peroxide Formulation With Azelaic Acid Formulation in the Treatment of Acne Vulgaris

Started Feb 2014
222 enrolled
Acne Vulgaris
NCT01555463Phase 3Completed

Safety and Efficacy of Azelaic Acid Foam, 15 % in Papulopustular Rosacea

Started Sep 2012
961 enrolled
Papulopustular Rosacea
NCT01430312Phase 1Completed

21 Day Irritancy Test of Azelaic Acid Pre-foam Formulation

Started Sep 2011
40 enrolled
Healthy
NCT01430533Phase 1Completed

Human Repeated Insult Patch Test (HRIPT) of Azelaic Acid Pre Foam Formulation

Started Sep 2011
240 enrolled
Healthy