NDAORALTABLET
Approved
May 1996
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Mechanism of Action
CLINICAL PHARMACOLOGY Nizatidine is a competitive, reversible inhibitor of histamine at the histamine H 2 -receptors, particularly those in the gastric parietal cells. Antisecretory Activity Effects on Acid Secretion Nizatidine significantly inhibited nocturnal gastric acid secretion for up to 12…