NDAINTRAVENOUSPOWDERPriority Review
Approved
Feb 2015
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
1
Data completeness
7/8 — Comprehensive
Priority Review
AVYCAZ (ceftazidime, avibactam) by AbbVie is [ see clinical pharmacology ( ) ]. Approved for the following infections caused by designated susceptible gram-negative microorganisms in adult, used in combination with metronidazole ( ) complicated urinary tract infections (cuti), including pyelonephritis ( ) hospital-acquired bacterial pneumonia and 19 more indications. First approved in 2015.
Drug data last refreshed 2h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
AVYCAZ is a fixed-dose combination of ceftazidime (a third-generation cephalosporin) and avibactam (a beta-lactamase inhibitor) administered intravenously to treat serious gram-negative bacterial infections. It targets resistant pathogens including Pseudomonas aeruginosa, Klebsiella pneumoniae, and Enterobacteriaceae across complicated urinary tract infections, hospital-acquired/ventilator-associated pneumonia, and intra-abdominal infections in adult patients. The avibactam component restores ceftazidime's effectiveness against beta-lactamase-producing organisms.
$16MPart D
Peak5.6 years to LOEEstablished peak-stage product with modest Part D uptake; commercial team likely focused on market maintenance and indication expansion rather than launch acceleration.
Mechanism of Action
[ see Clinical Pharmacology ( ) ].
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.