BLAINTRAVENOUSINJECTABLE2 Generics Approved
Approved
Jan 2025
Lifecycle
Growth
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
5/8 — Partial
AVTOZMA (tocilizumab) by Celltrion is interleukin 6 receptor antagonists [moa]. Approved for interleukin-6 receptor antagonist [epc]. First approved in 2025.
Drug data last refreshed 1h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
AVTOZMA (tocilizumab) is a monoclonal antibody targeting the interleukin-6 receptor, approved by the FDA on January 24, 2025. It is a biosimilar to Roche's ACTEMRA and works by blocking IL-6 signaling to reduce inflammatory responses. The drug is administered intravenously and is indicated for conditions driven by IL-6 pathway dysregulation, including rheumatoid arthritis and other inflammatory diseases.
Growth
As a newly approved biosimilar in growth phase, AVTOZMA presents expansion opportunities for commercial teams, particularly in market access, health economics, and rapid penetration strategies against established competitors.
Mechanism of Action
Interleukin 6 Receptor Antagonists
Pharmacologic Class:
Interleukin-6 Receptor Antagonist
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
A Study Evaluating the Prophylactic Use of Tocilizumab to Prevent Cytokine Release Syndrome With Ramantamig Administration in Participants With Relapsed/Refractory Multiple Myeloma
Started Jul 2026
230 enrolled
Multiple Myeloma
Adult Outpatient Linvoseltamab With Tocilizumab Prophylaxis to Mitigate the Risk of Cytokine Release Syndrome (CRS)
Started Jul 2026
30 enrolled
Relapsed/Refractory Multiple Myeloma (RRMM)
Tocilizumab Discontinuation Versus Dose Reduction for Patients With Well-Controlled Giant Cell Arteritis
Started Dec 2025
78 enrolled
Giant Cell Arteritis (GCA)
RCT of Tocilizumab for Anti-MDA5+DM
Started Nov 2025
110 enrolled
Dermatomyositis
Interleukin-6 Guided Treatment With Dexamethasone or Tocilizumab in Patients Hospitalized With Acute Respiratory Symptoms - a Feasibility Study
Started Oct 2025
60 enrolled
Acute Hypoxemic Respiratory Failure
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.