AVTOZMA
GrowthmAbBLAINTRAVENOUSINJECTABLE
Approved
Jan 2025
Lifecycle
Growth
Competitive Pressure
30/100
Data completeness
4/8 — Partial
AVTOZMA by Celltrion is membrane-bound il-6 receptors (sil-6r and mil-6r), and have been shown to inhibit il-6-mediated signaling through these receptors. Approved for more disease-modifying anti-rheumatic drugs (dmards), giant cell arteritis (gca) in adult patients, active polyarticular juvenile idiopathic arthritis in patients 2 years of age and 9 more indications. First approved in 2025.
Drug data last refreshed 36m ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
AVTOZMA (tocilizumab) is a monoclonal antibody that antagonizes the interleukin-6 (IL-6) receptor, reducing inflammatory signaling in autoimmune and inflammatory conditions. It is administered intravenously and represents a biosimilar entry to the tocilizumab market. The drug is indicated for IL-6 receptor-mediated inflammatory diseases, with primary use in rheumatoid arthritis and other autoimmune conditions.
Growth
Recent launch (January 2025) as a biosimilar entry signals building commercial infrastructure and field team expansion to capture market share from established competitors.
Mechanism of Action
membrane-bound IL-6 receptors (sIL-6R and mIL-6R), and have been shown to inhibit IL-6-mediated signaling through these receptors. IL-6 is a pleiotropic pro-inflammatory cytokine produced by a variety of cell types including T- and B-cells, lymphocytes, monocytes and fibroblasts. IL-6 has been…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.