NDAVAGINALCREAM
Approved
Jun 1965
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
6
Data completeness
2/8 — Basic
Drug data last refreshed 13h ago · AI intelligence enriched 2mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
AVC is a vaginal cream formulation of sulfanilamide, a sulfonamide antimicrobial agent approved in 1965 for topical vaginal use. It is indicated for treating vaginal infections caused by susceptible organisms. The drug works as a broad-spectrum antimicrobial that inhibits bacterial growth in the vaginal environment.
LOE Approaching
This legacy product faces approaching loss of exclusivity with moderate competitive pressure (30%), indicating a contracting team and focus on cost management rather than expansion.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (6)
KONECT RESILIA Aortic Valved Conduit (AVC) Real-world Study Assessing Safety and Performance
Started Jun 2026
250 enrolled
Aortic Valve Disease
A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Started Sep 2024
274 enrolled
Geographic AtrophyMacular Degeneration
A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Started Mar 2023
305 enrolled
Geographic Atrophy
AAVCAGsCD59 for the Treatment of Wet AMD
Started Sep 2018
25 enrolled
Wet Age-related Macular Degeneration
Treatment of Advanced Dry Age Related Macular Degeneration With AAVCAGsCD59
Started Mar 2017
17 enrolled
Dry Age-related Macular Degeneration
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.