NDAINTRAMUSCULAR, SUBCUTANEOUSSOLUTION
Approved
Aug 2012
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
20
Data completeness
6/8 — Strong
AUVI-Q (epinephrine) by Fresenius Kabi is adrenergic alpha-agonists [moa]. First approved in 2012.
Drug data last refreshed 16h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
AUVI-Q is an auto-injector formulation of epinephrine, a rapid-acting alpha-adrenergic agonist used for emergency treatment of anaphylaxis. It works by stimulating adrenergic receptors to reverse the physiological effects of anaphylaxis, including airway constriction and cardiovascular collapse. The product is delivered via intramuscular or subcutaneous injection in a pre-filled solution format.
$0.719MPart D
PeakStable
11.1 years to LOEAUVI-Q is at peak lifecycle with modest Part D penetration; commercial teams are focused on maintaining market position and defending against generic/competitive threats rather than growth expansion.
Mechanism of Action
Adrenergic alpha-Agonists
Pharmacologic Class:
alpha-Adrenergic Agonist
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
Pharmacokinetics and Safety of a Single Dose of Epinephrine Nasal Spray in Paediatric Allergy Patients
Started Sep 2026
44 enrolled
EpinephrineHypersensitivity, ImmediateAnaphylaxis
Continuous Versus Bolus Norepinephrine Administration to Treat Postinduction Hypotension
Started May 2026
446 enrolled
Postinduction Hypotension
Study Comparing Glycerin With 1% Lidocaine and Epinephrine Versus Glycerin With 1% Lidocaine Without Epinephrine for the Sclerotherapy of Leg Telangiectasias
Started Feb 2026
20 enrolled
Leg Veins
Hemodynamic Effects of Norepinephrine Reduction on Critical Closing Pressure in Distributive Shock
Started Sep 2025
30 enrolled
Distributive ShockHemodynamic AssessmentCritical Illness
Pneumatic Leg Compression and Norepinephrine Requirements in Patients Having Non-cardiac Surgery
Started May 2025
238 enrolled
Hypotension During Surgery
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.