AUBAGIO

Peak

teriflunomide

NDAORALTABLET
Approved
Sep 2012
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
20

Mechanism of Action

Dihydroorotate Dehydrogenase Inhibitors

Pharmacologic Class:

Pyrimidine Synthesis Inhibitor

Clinical Trials (5)

NCT05147220Phase 3Active Not Recruiting

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Started Dec 2021
1,001 enrolled
Relapsing Multiple Sclerosis
NCT05156281Phase 3Active Not Recruiting

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Started Dec 2021
1,011 enrolled
Relapsing Multiple Sclerosis
NCT04586023Phase 3Active Not Recruiting

Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)

Started Mar 2021
751 enrolled
Relapsing Multiple Sclerosis
NCT05075499N/AUnknown

Immune Response to COVID-19 Vaccine in Multiple Sclerosis Patients Treated With Teriflunomide and Alemtuzumab

Started Mar 2021
70 enrolled
Multiple Sclerosis
NCT04586010Phase 3Active Not Recruiting

A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)

Started Mar 2021
746 enrolled
Relapsing Multiple Sclerosis

Loss of Exclusivity

LOE Date
Aug 4, 2034
102 months away
Patent Expiry
Aug 4, 2034

Patent Records (5)

Patent #ExpiryTypeUse Code
6794410
Sep 12, 2026
U-1285
6794410*PED
Mar 12, 2027
8802735
Sep 14, 2030
Product
8802735*PED
Mar 14, 2031
9186346
Feb 4, 2034
U-1786