NDAINHALATIONAEROSOL, METERED3 Generics Approved
Approved
Nov 2004
Lifecycle
Peak
Competitive Pressure
38/100
Clinical Trials
8
Data completeness
5/8 — Partial
Drug data last refreshed 20h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ATROVENT HFA (ipratropium bromide) is a metered-dose inhaler containing an anticholinergic agent approved for chronic obstructive pulmonary disease (COPD). It works by antagonizing acetylcholine at neuromuscular junctions in the lung, inhibiting vagally-mediated reflexes and reducing airway secretions. As a quaternary amine, it has minimal systemic absorption and reduced anticholinergic side effects compared to tertiary amines. The product is positioned as a maintenance bronchodilator in COPD management, often used alongside beta-2 agonists for combination therapy.
$0.1BPart D
3.7 years to LOEMechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (8)
Ipratropium Bromide in Peri-Operative COPD
Started Oct 2013
192 enrolled
Pulmonary Disease, Chronic Obstructive
Study to Assess the Effect of Salbutamol and Ipratropium Bromide in Chronic Obstructive Pulmonary Disease (COPD) Patients
Started Jun 2008
6 enrolled
COPD
Ipratropium Bromide/Salbutamol Delivered by the Respimat® Inhaler Compared to Ipratropium Bromide Respimat®, COMBIVENT® Inhalation Aerosol and Placebo in Adults With Chronic Obstructive Pulmonary Disease
Started Oct 2002
1,118 enrolled
Pulmonary Disease, Chronic Obstructive
Study of the Comparability of Ipratropium Bromide Hydrofluoroalkane (HFA)-134a Inhalation Aerosol to the Market Standard, Atrovent® Chlorofluorocarbon (CFC) Inhalation Aerosol, in Patients With Chronic Obstructive Pulmonary Disease
Started Oct 2000
41 enrolled
Pulmonary Disease, Chronic Obstructive
Trial to Determine the Comparability of Ipratropium Bromide Hydrofluoroalkane (HFA)-134a Inhalation Aerosol to ATROVENT® Chlorofluorocarbon (CFC) Inhalation Aerosol, in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Started Oct 2000
30 enrolled
Pulmonary Disease, Chronic Obstructive
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.