NDAORALTABLET
Approved
Sep 1977
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
5
Mechanism of Action
CLINICAL PHARMACOLOGY Studies in healthy volunteers show that in single high doses Ativan (lorazepam) has a tranquilizing action on the central nervous system with no appreciable effect on the respiratory or cardiovascular systems. Ativan (lorazepam) is readily absorbed with an absolute…
Pharmacologic Class:
Benzodiazepine
Clinical Trials (5)
Phase 1 Study to Characterize the Safety and Pharmacokinetics of Single Intravenous Dose of Lorazepam in Healthy Japanese Adult Subjects
Started Jan 2014
8 enrolled
Healthy
A Study of the Effect of LY2216684 on Lorazepam
Started Dec 2010
28 enrolled
Major Depressive Disorder
Seizure Therapy With Intravenous Levetiracetam and Lorazepam
Started Jan 2008
0Seizures
GEM 1.5 mg b.i.d. to 4.5 mg b.i.d. Versus Lorazepam in GAD (0777-026)
Started Nov 2002
38 enrolled
Anxiety Disorder
A Study of Risperidone in Combination With Lorazepam Compared With Standard Therapy for Emergency Treatment of Schizophrenic Patients
Started Jun 2001
226 enrolled
SchizophreniaPsychotic DisordersEmergency Treatment