BLAINTRAVENOUSINJECTABLE
Approved
Dec 2018
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
1
Mechanism of Action
L-asparaginase is an enzyme that catalyzes the conversion of the amino acid L-asparagine into aspartic acid and ammonia. The pharmacological effect of ASPARLAS is thought to be based on the killing of leukemic cells due to depletion of plasma asparagine. Leukemic cells with low expression of…
Pharmacologic Class:
Asparagine-specific Enzyme
Indications (1)
Clinical Trials (1)
Calaspargase Pegol-Mnkl and Cobimetinib for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer
Started Aug 2022
15 enrolled
Locally Advanced Pancreatic AdenocarcinomaMetastatic Pancreatic AdenocarcinomaStage II Pancreatic Cancer AJCC v8+4 more