BLAINJECTIONINJECTABLEPriority Review
Approved
Oct 2009
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
5/8 — Partial
Priority Review
ARZERRA (ofatumumab) by Novartis is cd20-directed antibody interactions [moa]. Approved for cd20-directed cytolytic antibody [epc]. First approved in 2009.
Drug data last refreshed 18h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ARZERRA (ofatumumab) is a CD20-directed monoclonal antibody approved in 2009 for B-cell malignancies and autoimmune conditions. It works by binding to CD20 on B-cell surfaces, triggering cytolytic destruction of B cells. The drug is administered as an intravenous or subcutaneous injection.
LOE Approaching
ARZERRA faces significant competitive pressure (score: 30/100) and declining market relevance; expect smaller brand teams and focus on defensive positioning.
Mechanism of Action
CD20-directed Antibody Interactions
Pharmacologic Class:
CD20-directed Cytolytic Antibody
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
A Study to Evaluate the Real-world Experience and Satisfaction Associated With Ofatumumab
Started Jan 2026
261 enrolled
Multiple Sclerosis
Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of a New Maintenance Dosing Regimen of Ofatumumab
Started Mar 2025
196 enrolled
Relapsing Multiple Sclerosis (RMS)
Kesimpta (Ofatumumab) in Greek Multiple Sclerosis Patients - an Observational Study
Started Dec 2024
160 enrolled
Relapsing Multiple Sclerosis (RMS)
Concentration of Ofatumumab in the Breast Milk of Lactating Women With Relapsing Forms of Multiple Sclerosis
Started Nov 2024
24 enrolled
Multiple Sclerosis
A Real-world Study Comparing the Effectiveness of Ofatumumab and Ocrelizumab Treatment in Multiple Sclerosis Patients
Started Oct 2024
2,604 enrolled
Multiple Sclerosis
Worked on ARZERRA at Novartis? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.