AROMASIN

LOE Approaching

exemestane

NDAORALTABLET
Approved
Oct 1999
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

Aromatase Inhibitors

Pharmacologic Class:

Aromatase Inhibitor

Clinical Trials (5)

NCT03659136Phase 2Completed

The XENERA™ 1 Study Tests Xentuzumab in Combination With Everolimus and Exemestane in Women With Hormone Receptor Positive and HER2-negative Breast Cancer That Has Spread

Started Nov 2018
103 enrolled
Breast Neoplasms
NCT03137368Phase 3Unknown

A Study to Evaluate Exemestane Tablets Combined With Ovarian Function Suppression/Ablation in Treatment of Premenopausal Breast Cancer Patients With CYP2D6*10 Mutations (STEP)

Started Aug 2018
300 enrolled
CYP2D6 Polymorphism
NCT03312738Phase 2Completed

A Study of Everolimus Plus Exemestane in Chinese Postmenopausal Women With Estrogen Receptor Positive, Locally Advanced, Recurrent, or Metastatic Breast Cancer After Recurrence or Progression on Non-steroidal Aromatase Inhibitor

Started Sep 2017
159 enrolled
Advanced Breast Cancer
NCT02990845Phase 1/2Terminated

Pembrolizumab and Exemestane/ Leuprolide in Premenopausal HR+/ HER2- Locally Advanced or Metastatic Breast Cancer

Started Sep 2017
16 enrolled
Premenopausal Breast Cancer
NCT02983604Phase 1/2Terminated

GS-5829 in Combination With Fulvestrant or Exemestane in Women With Advanced Estrogen Receptor Positive, HER2 Negative-Breast Cancer

Started Jan 2017
14 enrolled
Advanced Estrogen Receptor Positive HER2- Breast Cancer