NDAORALTABLET
Approved
Dec 1995
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
5/8 — Partial
ARIMIDEX (anastrozole) by ANI Pharmaceuticals is aromatase inhibitors [moa]. First approved in 1995.
Drug data last refreshed 26m ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ARIMIDEX (anastrozole) is an oral aromatase inhibitor used primarily in hormone receptor-positive breast cancer treatment by reducing estrogen production. It works by blocking the aromatase enzyme, which converts androgens to estrogen in postmenopausal women. This mechanism makes it a cornerstone therapy in endocrine-sensitive breast cancer management.
$0.004BPart D
LOE ApproachingDeclining
Team focus shifts from growth to lifecycle management, defense, and line extensions; expect smaller commercial footprint as generics enter.
Mechanism of Action
Aromatase Inhibitors
Pharmacologic Class:
Aromatase Inhibitor
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
A Window-of-Opportunity Trial of Giredestrant +/- Triptorelin vs. Anastrozole + Triptorelin in Premenopausal Patients With ER-positive/HER2-negative Early Breast Cancer
Started Jan 2024
231 enrolled
Breast Cancer
A Trial Using ARV-471 or Anastrozole in Post-Menopausal Women With Breast Cancer Prior to Surgery
Started Feb 2023
152 enrolled
Breast Cancer
Prediction of Treatment Efficacy of the Combination of Palbociclib/(Letrozole or Anastrozole) in First Line Metastatic Women With Luminal, HER2 Negative Advanced Breast Cancer, Using Infrared Laser Spectroscopy Analysis on Liquid Biopsies.
Started Dec 2022
80 enrolled
Hormonal Receptors Positive, HER2 Negative, Advanced Breast Cancer
A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease
Started Jan 2021
1,371 enrolled
ER-Positive HER2-Negative Breast Cancer
Onapristone and Anastrozole for the Treatment of Refractory Hormone Receptor Positive Endometrial Cancer
Started Jan 2021
14 enrolled
Refractory Endometrial AdenocarcinomaRefractory Endometrial CarcinomaRefractory Endometrial Clear Cell Adenocarcinoma+4 more
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.