ARIDOL KIT

LOE Approaching

mannitol

NDAINHALATIONPOWDER
Approved
Oct 2010
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
9

Mechanism of Action

12.1 Mechanism of Action The precise mechanisms through which inhaled mannitol causes bronchoconstriction are not known. 12.2 Pharmacodynamics The response to inhaled mannitol is reported as the delivered dose of mannitol causing a 15% reduction in FEV 1 and is expressed as PD 15 . 12.3…

Indications (1)

Clinical Trials (5)

NCT05555290Phase 3Completed

PT027 Compared to PT007 in Patients With Asthma With Mannitol-induced Acute Airway Obstruction

Started Sep 2022
190 enrolled
Asthma
NCT02386449Phase 4Completed

A Study Comparing Picoprep With Mannitol and Bisacodyl for Colon Cleansing in Preparation for Colonoscopy

Started Feb 2015
184 enrolled
Bowel Preparation
NCT04534465Phase 4Completed

Study to Gather Information on the Acceptability of a New Flavor System With Increasing Levels of 2, 4, 6 g or Higher of Mannitol for PEG 3350 in Subjects Having Infrequent Bowel Movements.

Started Feb 2013
50 enrolled
Constipation
NCT01111682Phase 3Terminated

Hypertonic Saline vs. Mannitol for Elevated Intercranial Pressure

Started Apr 2010
5 enrolled
Traumatic Brain InjuryElevated Intracranial Pressure
NCT00983398Phase 1/2Unknown

Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors

Started Jul 2009
17 enrolled
Central Nervous System Embryonal NeoplasmEmbryonal Tumor With Multilayered Rosettes, C19MC-AlteredGerm Cell Tumor+7 more