AREDIA

LOE Approaching

pamidronate disodium

NDAINJECTIONINJECTABLE
Approved
Sep 1998
Lifecycle
LOE Approaching
Competitive Pressure
30/100

Mechanism of Action

resorption. Although the mechanism of antiresorptive action is not completely understood, several factors are thought to contribute to this action. Pamidronate disodium adsorbs to calcium phosphate (hydroxyapatite) crystals in bone and may block dissolution of this mineral component of bone. In…