APTIVUS
LOE ApproachingNDAORALCAPSULEPriority Review
Approved
Jun 2005
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
3
Data completeness
4/8 — Partial
Priority Review
APTIVUS by Boehringer Ingelheim is 12. First approved in 2005.
Drug data last refreshed 10h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
APTIVUS (tipranavir) is an oral HIV protease inhibitor approved in 2005 for treatment-experienced patients with HIV-1 infection. It works by blocking the viral protease enzyme, preventing HIV replication and viral maturation. The drug is indicated for protease inhibitor-experienced patients as part of combination antiretroviral therapy.
LOE Approaching
Product faces patent expiration with moderate competitive pressure (30/100), indicating a contracting team and transition focus toward managed care and generic erosion strategies.
Mechanism of Action
12.1 Mechanism of Action Tipranavir is an antiretroviral drug [ see ]. 12.2 Pharmacodynamics ECG Evaluation The effect of APTIVUS/ritonavir on the QTcF interval was measured in a study in which 81 healthy subjects received the following treatments twice daily for 2.5 days: APTIVUS/ritonavir (500…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.