APRETUDE

Peak

cabotegravir

NDAINTRAMUSCULARSUSPENSION, EXTENDED RELEASEPriority Review
Approved
Dec 2021
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
20

Mechanism of Action

HIV-1 antiretroviral drug [see Microbiology ()] in a long-acting formulation.

Clinical Trials (5)

NCT07275606Phase 1/2Not Yet Recruiting

A Study to Investigate Cabotegravir for Neonates Exposed to HIV-1

Started Mar 2026
66 enrolled
HIV Infections
NCT07370649N/ANot Yet Recruiting

Long-Acting Cabotegravir and Rilpivirine in People Living With HIV-1 Subtype A6: A Real-World Retrospective Study

Started Feb 2026
250 enrolled
Human Immunodeficiency Virus (HIV)-1 InfectionHIV-1 Subtype A6 InfectionHIV-1 Subtype B Infection+1 more
NCT07199335Phase 4Not Yet Recruiting

Long-acting Cabotegravir Injectable Pre-exposure Prophylaxis for People Who Inject Drugs

Started Nov 2025
100 enrolled
HIVSubstance Use Disorder (SUD)Injection Drug Use
NCT05835635N/ANot Yet Recruiting

Switch From Oral Therapy to Long-acting Injectable Cabotegravir + Rilpivirine

Started May 2025
50 enrolled
Patient SatisfactionPatient PreferenceQuality of Life+1 more
NCT06970223Phase 1Active Not Recruiting

A Study to Investigate if Long Acting Cabotegravir (CAB) and Lenacapavir (LEN) Injections Are Tolerable and Acceptable When Administered to Healthy Adults Without HIV

Started Apr 2025
65 enrolled
HIV Infections

Loss of Exclusivity

LOE Date
Sep 15, 2031
67 months away
Patent Expiry
Sep 15, 2031
Exclusivity Expiry
Jan 21, 2026

Patent Records (4)

Patent #ExpiryTypeUse Code
10927129
Apr 28, 2026
SubstanceProduct
8410103
Feb 4, 2031
SubstanceProduct
11224597
Sep 15, 2031
Product
12138264
Sep 15, 2031
Product