NDAORALCAPSULEPriority Review
Approved
Nov 1971
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
4
Mechanism of Action
CLINICAL PHARMACOLOGY Flucytosine is rapidly and virtually completely absorbed following oral administration. ANCOBON is not metabolized significantly when given orally to man. Bioavailability estimated by comparing the area under the curve of serum concentrations after oral and intravenous…
Pharmacologic Class:
Nucleoside Analog Antifungal
Clinical Trials (4)
Liposomal Amphotericin B and Flucytosine Antifungal Strategy for Talaromycosis (LAmB-FAST)
Started Apr 2026
428 enrolled
Talaromycosis
Safety Study of Fluconazole in Combination With Flucytosine for the Treatment of Early Cryptococcal Infection
Started Sep 2013
Trial of TG4023 Combined With Flucytosine in Liver Tumors
Started Sep 2009
A Pilot Study of Fluconazole Plus Flucytosine for the Treatment of AIDS Patients With Acute Cryptococcal Meningitis.
64 enrolled
Meningitis, CryptococcalHIV Infections