AMMONUL

LOE Approaching

sodium benzoate; sodium phenylacetate

NDAINTRAVENOUSSOLUTIONPriority Review
Approved
Feb 2005
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1

Mechanism of Action

enzymes: N -acetylglutamate synthetase (NAGS), carbamyl phosphate synthetase (CPS), argininosuccinate synthetase (ASS), ornithine transcarbamylase (OTC), argininosuccinate lyase (ASL), or arginase (ARG). Sodium phenylacetate and sodium benzoate are metabolically active compounds that can serve as…

Clinical Trials (1)

NCT00597909Phase 2Terminated

Efficacy and Safety Study of Ammonul® in Patients With Grade 3 or 4 Hepatic Encephalopathy

Started Dec 2007
1 enrolled
Hepatic Encephalopathy