AMLODIPINE BESYLATE

Post-LOE

amlodipine besylate

ANDAORALTABLET
Approved
Sep 2007
Lifecycle
Post-LOE
Competitive Pressure
30/100
Clinical Trials
3

Mechanism of Action

(calcium ion antagonist or slow-channel blocker) that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. Experimental data suggest that amlodipine binds to both dihydropyridine and nondihydropyridine binding sites. The contractile processes of cardiac…

Clinical Trials (3)

NCT02940548Phase 4Terminated

Nifedipine GITS and Amlodipine Besylate on Recovery of Blood Pressure Rhythm and Arterial Stiffness

Started Dec 2016
99 enrolled
Hypertension
NCT01138826Phase 1Completed

Bioavailability Study Comparing 10 Mg Amlodipine Besylate Orally Disintegrating Tablet (ODT) And 10 Mg Amlodipine Besylate Tablets

Started May 2010
18 enrolled
Healthy Volunteers
NCT00136851Phase 4Completed

Study Comparing the Efficacy of Amlodipine Besylate/Benazepril Versus Amlodipine in the Treatment of Severe Hypertension

Started Dec 2004
259 enrolled
Hypertension