AMLODIPINE BESYLATE AND BENAZEPRIL HYDROCHLORIDE
Post-LOEamlodipine besylate and benazepril hydrochloride
ANDAORALCAPSULE
Approved
Apr 2010
Lifecycle
Post-LOE
Competitive Pressure
30/100
Mechanism of Action
angiotensin-converting enzyme (ACE) in human subjects and in animals. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance angiotensin II. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex. Inhibition of ACE results…