AMINOPHYLLIN

LOE Approaching

aminophylline

NDAORALTABLET
Approved
Apr 1940
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
2

Mechanism of Action

Mechanism of Action: Theophylline has two distinct actions in the airways of patients with reversible obstruction; smooth muscle relaxation (i.e., bronchodilation) and suppression of the response of the airways to stimuli (i.e., nonbronchodilator prophylactic effects). While the mechanisms of…

Indications (1)

Clinical Trials (2)

NCT01794078Phase 1Completed

A Study to Test the Safety of Combined Dosing With Aminophylline and Ambrisentan in Exercising Healthy Human Volunteers at Simulated High Altitude

Started Sep 2013
92 enrolled
Acute Mountain Sickness and Fatigue
NCT01336140Phase 4Completed

Attenuation of the Side Effect Profile of Regadenoson: Study With Aminophylline in Patients With Severe Kidney Disease Undergoing Myocardial Perfusion Imaging

Started Jun 2011
300 enrolled
Patients With Severe Chronic Kidney Disease Being Evaluated With Nuclear Stress Testing of the Heart Using the Stress Agent Regadenoson