NDAINJECTIONINJECTABLE
Approved
Sep 1982
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
2
Data completeness
4/8 — Partial
AMIDATE (etomidate) by Pfizer is clinical pharmacology etomidate is a general anesthetic without analgesic activity. First approved in 1982.
Drug data last refreshed 16h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
AMIDATE (etomidate) is a rapid-acting intravenous general anesthetic with no analgesic activity, producing unconsciousness within one minute with a brief duration of 3-5 minutes. It is used for induction and maintenance of anesthesia in surgical and procedural settings. Etomidate works via CNS depression and is characterized by minimal cardiovascular effects compared to barbiturate alternatives.
LOE Approaching
Product approaching loss of exclusivity with legacy market positioning; team likely focused on cost containment and generic transition planning rather than growth initiatives.
Mechanism of Action
CLINICAL PHARMACOLOGY Etomidate is a general anesthetic without analgesic activity. Intravenous injection of etomidate produces anesthesia characterized by a rapid onset of action, usually within one minute. Duration of anesthesia is dose dependent but relatively brief, usually three to five…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.