NDAORALCAPSULE
Approved
Feb 2007
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
4/8 — Partial
ALLI (orlistat) by GSK is lipase inhibitors [moa]. First approved in 2007.
Drug data last refreshed 6h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ALLI (orlistat) is an oral intestinal lipase inhibitor approved in 2007 for weight management in adults. It works by blocking the absorption of dietary fats in the gastrointestinal tract, reducing caloric intake. The drug is indicated as an adjunct to a reduced-calorie diet and exercise program.
LOE Approaching
As LOE approaches, the commercial team is transitioning from growth maintenance to line extension or lifecycle management strategies, signaling consolidation of field and marketing resources.
Mechanism of Action
Lipase Inhibitors
Pharmacologic Class:
Intestinal Lipase Inhibitor
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
ALLIANCE Mitral: Safety and Effectiveness of SAPIEN X4 Transcatheter Heart Valve - Mitral
Started Jan 2027
125 enrolled
Mitral RegurgitationMitral Valve DiseaseMitral Stenosis
Single Arm, Monocentric, Pilot Feasibility Study on an Interactive Virtual Reality Program in 20 Complex In-clinic Palliative Care Patients
Started Sep 2026
20 enrolled
Palliative CareRefractory PainAnxiety+3 more
Efficacy and Safety of Human Urinary Kallidinogenase Combined With Reteplase Intravenous Thrombolysis in the Treatment of Acute Ischemic Stroke
Started May 2026
220 enrolled
Acute Ischemic Stroke
Palliative Care Intervention to Improve Health Related Quality of Life for Patients on Long-Term LVAD Support
Started Mar 2026
90 enrolled
Advanced Heart FailureMechanical Circulatory SupportLeft Ventricular Assist Device+1 more
Effects of a Neurorehabilitation Program Based on CIMT and Non-invasive Neuromodulation Through C-tDCS on the Recovery of Paretic Upper Limb Function, Quality of Life, and Therapeutic Alliance in Women From the Araucanía Region Who Suffered a Stroke (CIMT + tDCS).
Started Mar 2026
24 enrolled
Stroke
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.