NDAINJECTIONINJECTABLE
Approved
Dec 1986
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
3/8 — Basic
ALFENTA (alfentanil hydrochloride) by Pfizer is clinical pharmacology alfenta (alfentanil hydrochloride) is an opioid analgesic with a rapid onset of action. First approved in 1986.
Drug data last refreshed 43m ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ALFENTA (alfentanil hydrochloride) is a potent, short-acting opioid analgesic administered by injection for perioperative analgesia and sedation. It works as a mu-opioid receptor agonist with rapid onset and offset kinetics, providing pain relief and hemodynamic stability during surgical procedures. The drug is used in anesthesia for procedures ranging from brief (30 minutes) to extended (60+ minutes) operations.
LOE Approaching
As LOE approaches, the brand team is likely focused on lifecycle extension and managing market transition; expect reduced headcount and shift toward generic transition planning.
Mechanism of Action
CLINICAL PHARMACOLOGY ALFENTA (alfentanil hydrochloride) is an opioid analgesic with a rapid onset of action. At doses of 8-40 mcg/kg for surgical procedures lasting up to 30 minutes, ALFENTA provides analgesic protection against hemodynamic responses to surgical stress with recovery times…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.