NDAINTRAVENOUSSOLUTION
Approved
Apr 2016
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
4/8 — Partial
AKOVAZ (ephedrine sulfate) by Dr. Reddy's Laboratories is α- and β-adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons. First approved in 2016.
Drug data last refreshed 7h ago · AI intelligence enriched 9h ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
AKOVAZ is an intravenous ephedrine sulfate solution approved in 2016 for acute hypotension management in perioperative and acute care settings. It functions as a sympathomimetic agent that activates α- and β-adrenergic receptors while indirectly releasing norepinephrine from sympathetic neurons, increasing arterial pressure, cardiac output, and peripheral resistance. This mechanism makes it a critical intervention for hemodynamic instability in acute clinical scenarios.
Peak
As a peak-stage acute care product with moderate competitive pressure (30), the brand team is likely focused on market penetration in hospital formularies and clinical utilization optimization.
Mechanism of Action
α- and β-adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons. Pressor effects by direct alpha- and beta-adrenergic receptor activation are mediated by increases in arterial pressures, cardiac output, and peripheral resistance. Indirect adrenergic…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Bioequivalence Study of Desloratadine and Pseudoephedrine Sulfate Extended-release Tablets Under Fasting Conditions
Started Apr 2006
34 enrolled
Healthy
Career Relevance
Working on AKOVAZ offers exposure to acute care commercialization, hospital formulary strategy, and intensive care clinical relationships—valuable experience for professionals targeting hospital-based pharmaceutical roles. However, the zero linked jobs and lack of active clinical development suggest a stable but not rapidly expanding career platform.
Hospital Account Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.