NDAINTRAVENOUSSOLUTION
Approved
Apr 2016
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
4/8 — Partial
AKOVAZ (ephedrine sulfate) by Dr. Reddy's Laboratories is α- and β-adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons. First approved in 2016.
Drug data last refreshed 15m ago · AI intelligence enriched 6d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
AKOVAZ (ephedrine sulfate) is an intravenous sympathomimetic amine that restores blood pressure in perioperative hypotension by activating α- and β-adrenergic receptors and triggering norepinephrine release from sympathetic neurons. It is administered as an IV solution and works through direct receptor activation and indirect sympathetic stimulation to increase arterial pressure, cardiac output, and peripheral resistance. The drug addresses acute hemodynamic instability in surgical and critical care settings.
Peak
Product is in peak commercial stage with moderate competitive pressure (30%), suggesting stable but mature market positioning with likely established field and commercial infrastructure.
Mechanism of Action
α- and β-adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons. Pressor effects by direct alpha- and beta-adrenergic receptor activation are mediated by increases in arterial pressures, cardiac output, and peripheral resistance. Indirect adrenergic…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Bioequivalence Study of Desloratadine and Pseudoephedrine Sulfate Extended-release Tablets Under Fasting Conditions
Started Apr 2006
34 enrolled
Healthy
Career Relevance
AKOVAZ currently has zero linked job openings on major pharma job boards, indicating a mature, stable team with limited active hiring. Career opportunities exist primarily in safety monitoring, physician education, and field-level market maintenance rather than growth-stage expansion roles.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.