NDAINTRAVENOUSSOLUTION
Approved
Apr 2016
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
4/8 — Partial
AKOVAZ (ephedrine sulfate) by Dr. Reddy's Laboratories is α- and β-adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons. First approved in 2016.
Drug data last refreshed 5h ago · AI intelligence enriched 4w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
AKOVAZ is an intravenous ephedrine sulfate solution approved in 2016 for treating hypotension by stimulating α- and β-adrenergic receptors and releasing norepinephrine from sympathetic neurons. It increases arterial pressure, cardiac output, and peripheral resistance through direct and indirect sympathomimetic mechanisms. The drug is indicated for acute hypotensive episodes in perioperative and critical care settings.
Peak
Peak lifecycle stage suggests stable commercial performance with established market presence; team focus likely on market maintenance and optimization.
Mechanism of Action
α- and β-adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons. Pressor effects by direct alpha- and beta-adrenergic receptor activation are mediated by increases in arterial pressures, cardiac output, and peripheral resistance. Indirect adrenergic…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Bioequivalence Study of Desloratadine and Pseudoephedrine Sulfate Extended-release Tablets Under Fasting Conditions
Started Apr 2006
34 enrolled
Healthy
Career Relevance
Working on AKOVAZ offers career exposure to acute-care and hospital-based pharmaceutical commercialization, with emphasis on healthcare provider engagement and clinical safety management. The peak lifecycle stage and moderate competitive environment suggest stable but competitive career roles with focus on market share defense and prescriber education.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.