AGGRENOX

LOE Approaching

aspirin; dipyridamole

NDAORALCAPSULE, EXTENDED RELEASEPriority Review
Approved
Nov 1999
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
8

Mechanism of Action

12.1 Mechanism of Action The antithrombotic action of AGGRENOX is the result of the additive antiplatelet effects of dipyridamole and aspirin. Dipyridamole Dipyridamole inhibits the uptake of adenosine into platelets, endothelial cells and erythrocytes in vitro and in vivo ; the inhibition occurs…

Clinical Trials (5)

NCT04410328Phase 3Completed

Aggrenox To Treat Acute Covid-19

Started Oct 2020
98 enrolled
Covid19
NCT01303445Phase 1Completed

Drug-drug Interaction Study of Aggrenox and Omeprazole in Normal Volunteers

Started Mar 2011
60 enrolled
Healthy
NCT00562588Phase 4Completed

EARLY 3-months Aggrenox Treatment Started Within 24 Hrs of Ischemic Stroke Onset vs. After One Week 100 mg ASA

Started Jul 2007
551 enrolled
Cerebrovascular Accident
NCT00311402Phase 3Completed

JASAP: Japanese Aggrenox Stroke Prevention vs. Aspirin Programme

Started Apr 2006
1,295 enrolled
Cerebrovascular Accident
NCT02273531Phase 1Completed

Bioequivalence of a New Asasantin Formulation Extended Release (ER) Compared to the Commercially Available Asasantin Formulation (Aggrenox®; Extended Release) in Healthy Male and Female Volunteers

Started Jan 2004
24 enrolled
Healthy