NDAINTRAMUSCULAR, INTRAVENOUS, SUBCUTANEOUSSOLUTION
Approved
Dec 2012
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
20
Data completeness
6/8 — Strong
ADRENALIN (epinephrine) by Pfizer is adrenergic alpha-agonists [moa]. First approved in 2012.
Drug data last refreshed 15h ago · AI intelligence enriched 18h ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ADRENALIN (epinephrine) is a small-molecule alpha-adrenergic agonist administered via intramuscular, intravenous, or subcutaneous injection. It is the standard emergency treatment for anaphylaxis and acute allergic reactions, working by stimulating alpha-adrenergic receptors to rapidly reverse life-threatening symptoms. The product addresses a critical, time-sensitive medical need with no viable alternatives in acute care settings.
$0.051BPart D
PeakStable
8.5 years to LOEPeak lifecycle with stable Medicare utilization indicates mature, essential franchise requiring defensive strategy and operational excellence rather than aggressive growth initiatives.
Mechanism of Action
Adrenergic alpha-Agonists
Pharmacologic Class:
alpha-Adrenergic Agonist
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
Continuous Versus Bolus Norepinephrine Administration to Treat Postinduction Hypotension
Started May 2026
446 enrolled
Postinduction Hypotension
Study Comparing Glycerin With 1% Lidocaine and Epinephrine Versus Glycerin With 1% Lidocaine Without Epinephrine for the Sclerotherapy of Leg Telangiectasias
Started Feb 2026
20 enrolled
Leg Veins
Hemodynamic Effects of Norepinephrine Reduction on Critical Closing Pressure in Distributive Shock
Started Sep 2025
30 enrolled
Distributive ShockHemodynamic AssessmentCritical Illness
Study Evaluating the Safety and Efficacy of Neffy or Intramuscular Adrenalin in Patients With Allergic Reactions After Oral Food Challenge or Allergen Immunotherapy
Started May 2025
600 enrolled
Allergic Reactions
Pneumatic Leg Compression and Norepinephrine Requirements in Patients Having Non-cardiac Surgery
Started May 2025
238 enrolled
Hypotension During Surgery
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.