ADLARITY

Peak

donepezil hydrochloride

NDATRANSDERMALSYSTEM
Approved
Mar 2022
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
20

Mechanism of Action

12.1 Mechanism of Action Current theories on the pathogenesis of the cognitive signs and symptoms of Alzheimer's disease attribute some of them to a deficiency of cholinergic neurotransmission. Donepezil hydrochloride is postulated to exert its therapeutic effect by enhancing cholinergic function.…

Clinical Trials (5)

NCT02448784N/ACompleted

Post-marketing Surveillance of Donepezil Hydrochloride - Investigation of Long Term Safety and Efficacy of Aricept as Well as Its Proper Use Information in Patients With Dementia With Lewy Bodies (DLB).

Started Apr 2015
591 enrolled
Dementia With Lewy Body Disease
NCT02660983Phase 4Completed

A Study of Donepezil Hydrochloride in Patients With Dementia Associated With Cerebrovascular Disease

Started Aug 2013
302 enrolled
Dementia Associated With Cerebrovascular Disease
NCT02162251N/ACompleted

Post-marketing Surveillance of Donepezil Hydrochloride Investigation of the Safety and Effectiveness of Combination Therapy of Donepezil Hydrochloride and Memantine Hydrochloride in Patients With Alzheimer's Disease

Started Jun 2013
3,482 enrolled
Alzheimer's Desease
NCT02162264N/ACompleted

Post-marketing Surveillance of Donepezil Hydrochloride -Investigation of the Factors That Affect Aricept Medication Persistence Rate and the Safety and Efficacy in Patients With Alzheimer's Disease in Clinical Practice

Started Jun 2013
8,662 enrolled
Alzheimer's Disease
NCT01539031Phase 3Completed

Compare the Efficacy and Safety of Donepezil Hydrochloride 23 mg Treatment With Continuation of Donepezil Hydrochloride 10 mg Treatment in Japanese Subjects With Severe Alzheimer's Disease

Started Mar 2012
351 enrolled
Alzheimer's Type Dementia

Loss of Exclusivity

LOE Date
Aug 11, 2038
151 months away
Patent Expiry
Aug 11, 2038

Patent Records (5)

Patent #ExpiryTypeUse Code
12161767
Dec 30, 2036
SubstanceProduct
U-3334
12168075
Dec 30, 2036
U-3334
11679086
May 26, 2037
U-3334
11103463
Jul 26, 2037
U-3334
9993466
Jul 26, 2037
Product