NDATRANSDERMALSYSTEM
Approved
Mar 2022
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
20
Data completeness
5/8 — Partial
ADLARITY (donepezil hydrochloride) by PharmaIN is 12. First approved in 2022.
Drug data last refreshed 1h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ADLARITY is a transdermal system formulation of donepezil hydrochloride, an acetylcholinesterase inhibitor approved in March 2022 for Alzheimer's disease. It works by increasing acetylcholine concentration through reversible inhibition of acetylcholinesterase, enhancing cholinergic neurotransmission to improve cognitive function. The transdermal delivery system offers an alternative to oral tablets, potentially improving adherence in elderly dementia patients.
$0.002BPart D
Peak12.1 years to LOEPeak-stage product with modest Part D penetration (4,391 claims in 2023) indicates early commercial traction; brand team size likely stable with focus on market expansion and differentiation versus generic oral donepezil.
Mechanism of Action
12.1 Mechanism of Action Current theories on the pathogenesis of the cognitive signs and symptoms of Alzheimer's disease attribute some of them to a deficiency of cholinergic neurotransmission. Donepezil hydrochloride is postulated to exert its therapeutic effect by enhancing cholinergic function.…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.