ADCETRIS (brentuximab vedotin) by Pfizer is cd30-directed antibody interactions [moa]. Approved for hodgkin lymphoma, anaplastic large cell lymphoma. First approved in 2011.
Drug data last refreshed 23h ago · AI intelligence enriched 2w ago
ADCETRIS (brentuximab vedotin) is a CD30-directed antibody-drug conjugate (ADC) that binds to CD30 antigen on tumor cells and delivers cytotoxic payload, inducing cell death. It is approved for multiple lymphomas including Hodgkin lymphoma, peripheral T-cell lymphomas, mycosis fungoides, and relapsed/refractory B-cell lymphomas. The drug can be used as monotherapy or in combination with chemotherapy regimens depending on indication and disease status.
Peak lifecycle product with modest Part D spending ($3M in 2023) indicates mature market penetration; supply chain and operational roles suggest focus on manufacturing efficiency and distribution optimization rather than commercial expansion.
CD30-directed Antibody Interactions
CD30-directed Immunoconjugate
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The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.
A Study of Brentuximab Vedotin With Doxorubicin, Vinblastine and Dacarbazine in Adults With Hodgkin Lymphoma in India
Open Label Extension Study of Brentuximab Vedotin in Early dcSSc
A Study in Adults With Cutaneous T-cell Lymphoma (CTCL) Retreated With Brentuximab Vedotin
A Study in Adults With Advanced Classical Hodgkin's Lymphoma (cHL) in Brazil Treated With Brentuximab Vedotin Together With Chemotherapy Compared to Chemotherapy Alone
PET Adapted Brentuximab Vedotin and Pembrolizumab in Combination With Doxorubicin and Dacarbazine in Classic Hodgkin Lymphoma
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Upgrade to Pro — $25/moPfizer is hiring 6 roles related to this product
ADCETRIS linked career opportunities are currently limited to supply chain internship roles, reflecting mature product lifecycle focused on manufacturing, distribution, and cost optimization rather than commercial development. The low linked job count (1 role) contrasts with peak lifecycle status, suggesting the product is well-established with stable team composition and limited expansion hiring at Pfizer.
1 open roles linked to this drug