BLAINJECTIONINJECTABLEPriority Review
Approved
Aug 2011
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
5/8 — Partial
Priority Review
ADCETRIS (brentuximab vedotin) by Pfizer is cd30-directed antibody interactions [moa]. First approved in 2011.
Drug data last refreshed 5h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ADCETRIS (brentuximab vedotin) is a CD30-directed antibody-drug conjugate (ADC) approved in 2011 for hematologic malignancies expressing CD30. It works by binding to CD30 on cancer cells and delivering a cytotoxic payload (monomethyl auristatin E) intracellularly. The drug targets both Hodgkin lymphoma and systemic anaplastic large-cell lymphoma (sALCL).
$0.003BPart D
PeakPeak-stage product with modest Part D footprint suggests stable but not expanding commercial infrastructure; team size likely rationalized post-launch ramp.
Mechanism of Action
CD30-directed Antibody Interactions
Pharmacologic Class:
CD30-directed Immunoconjugate
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
Real-life Experience of Brentuximab Vedotin Plus CHP as First-line Treatment of CD30+ Peripheral T-cell Lymphomas in Spain
Started Feb 2026
100 enrolled
CD30-Positive Peripheral T-Cell Lymphoma
A Study of Brentuximab Vedotin With Doxorubicin, Vinblastine and Dacarbazine in Adults With Hodgkin Lymphoma in India
Started Aug 2024
124 enrolled
Hodgkin Lymphoma
Open Label Extension Study of Brentuximab Vedotin in Early dcSSc
Started Feb 2024
11 enrolled
Diffuse Cutaneous Systemic Sclerosis
A Study in Adults With Cutaneous T-cell Lymphoma (CTCL) Retreated With Brentuximab Vedotin
Started Feb 2024
26 enrolled
T-Cell Lymphoma
A Study in Adults With Advanced Classical Hodgkin's Lymphoma (cHL) in Brazil Treated With Brentuximab Vedotin Together With Chemotherapy Compared to Chemotherapy Alone
Started Dec 2023
0Hodgkin Lymphoma
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.