ANDATOPICALGEL
Approved
Oct 2014
Lifecycle
Post-LOE
Competitive Pressure
30/100
Clinical Trials
4
Mechanism of Action
12.1 Mechanism of Action Adapalene binds to specific retinoic acid nuclear receptors but does not bind to cytosolic receptor protein. Biochemical and pharmacological profile studies have demonstrated that adapalene is a modulator of cellular differentiation, keratinization, and inflammatory…
Pharmacologic Class:
Retinoid
Clinical Trials (4)
Clindamycin Phosphate, Adapalene, and Benzoyl Peroxide Triple Combination Gel in Canadian Patients With Acne Vulgaris
Started Oct 2025
A Study to Evaluate the Efficacy and Safety of Adapalene-Clindamycin Combination Gel in the Treatment of Acne Vulgaris
Started Aug 2018
1,617 enrolled
Acne Vulgaris
Compound Adapalene and Clindamycin Hydrochloride Gel in Treatment of Patients With Acne
Started Mar 2015
245 enrolled
Acne
Bioequivalence of Adapalene Topical Gel in Patients With Acne Vulgaris
Started Jul 2007
601 enrolled
Acne Vulgaris