ADAKVEO

PeakmAb

crizanlizumab

BLAINJECTIONINJECTABLEPriority Review
Approved
Nov 2019
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
16

Mechanism of Action

P-Selectin Blockers

Pharmacologic Class:

Selectin Blocker

Clinical Trials (5)

NCT06439082Phase 3Recruiting

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

Started Oct 2024
315 enrolled
Sickle Cell Disease
NCT05469828Phase 1/2Not Yet Recruiting

Crizanlizumab Improves Tissue Oxygen Supply Demand Matching in Patients With Sickle Cell Anemia

Started Jul 2024
30 enrolled
Sickle Cell Disease
NCT06662825N/ACompleted

Real World Patient Characteristics and Treatment Patterns From Crizanlizumab Use: Preliminary Analysis From Select Sickle Cell Centers

Started Dec 2022
376 enrolled
Sickle Cell Disease
NCT05334576N/AUnknown

Study of Crizanlizumab for Prevention of Silent Cerebral Infarcts in SCA

Started Aug 2022
31 enrolled
Sickle Cell Disease
NCT05020873N/ATerminated

Prospective, Observational Study in Sickle Cell Disease Patients on Crizanlizumab Treatment in Middle East Countries and India

Started Nov 2021
44 enrolled
Sickle Cell Disease