ACZONE

Peak

dapsone

Almirall

NDATOPICALGEL

Approved

Feb 2016

Lifecycle

Peak

Competitive Pressure

0/100

Clinical Trials

Mechanism of Action

12.1 Mechanism of Action The mechanism of action of dapsone gel in treating acne vulgaris is not known. 12.3 Pharmacokinetics In a pharmacokinetic study, male and female subjects 16 years of age or older with acne vulgaris (N=19) applied 2 grams of ACZONE Gel, 7.5% to the face, upper chest, upper…

Pharmacologic Class:

Sulfone

Clinical Trials (4)

NCT01931150Phase 3Completed

Study of Prophylactic Topical Dapsone 5% Gel Versus Moisturizer for Cetuximab-induced Papulopustular (Acneiform) Rash in Patients With mCRC or HNSCC Without Previous or Concurrent RT

Started Aug 2013

11 enrolled

Cetuximab-induced Papulopustular (Acneiform) Rash Who HaveMetastatic Colorectal Cancer or Head and Neck Squamous Cell Carcinoma

NCT00344006Phase 3Completed

Chlorproguanil-Dapsone-Artesunate Versus COARTEM For Uncomplicated Malaria

Started Jun 2006

1,395 enrolled

Malaria, Falciparum

NCT00371735Phase 3Completed

Chlorproguanil-Dapsone-Artesunate (CDA) Versus Chlorproguanil-Dapsone (LAPDAP) For Uncomplicated Malaria

Started Apr 2006

900 enrolled

Malaria, Falciparum

NCT00000802Phase 3Completed

A Randomized, Comparative Study of Daily Dapsone and Daily Atovaquone for Prophylaxis Against PCP in HIV-Infected Patients Who Are Intolerant of Trimethoprim and/or Sulfonamides