ACTIMMUNE

LOE Approaching

interferon gamma-1b

BLASINGLE-USEVIAL
Approved
Feb 1999
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
4

Mechanism of Action

interferon-stimulated genes. The three major groups of interferons (alpha, beta, gamma) have partially overlapping biological activities that include immunoregulation such as increased resistance to microbial pathogens and inhibition of cell proliferation. Type 1 interferons (alpha and beta) bind…

Pharmacologic Class:

Interferon gamma

Clinical Trials (4)

NCT02797080Phase 3Completed

Long-Term Safety Extension Study of ACTIMMUNE® (Interferon γ-1b) in Children and Young Adults With Friedreich's Ataxia

Started Jun 2016
38 enrolled
Friedreich's Ataxia
NCT02593773Phase 3Completed

Safety, Tolerability and Efficacy of ACTIMMUNE® Dose Escalation in Friedreich's Ataxia Study

Started Dec 2015
86 enrolled
Friedreich's Ataxia
NCT02415127Phase 3Completed

Safety, Tolerability and Efficacy of ACTIMMUNE® Dose Escalation in Friedreich's Ataxia

Started Jun 2015
92 enrolled
Friedreich's Ataxia
NCT01965327Phase 2Completed

Interferon Gamma-1b in Friedreich Ataxia (FRDA)

Started Aug 2013
12 enrolled
Friedreich Ataxia