NDAINJECTIONINJECTABLE
Approved
Mar 1952
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
15
Data completeness
4/8 — Partial
ACTH (corticotropin) by Pfizer is gram-negative coccobacillus. Approved for infantile spasms, epilepsy. First approved in 1952.
Drug data last refreshed 1w ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ACTH (corticotropin) is a peptide hormone therapeutic approved in 1952 for infantile spasms and epilepsy, administered by injection. It works through endocrine mechanisms to modulate immune and neurological function, though the precise mechanism in seizure control remains incompletely understood. The product represents one of the oldest FDA-approved treatments in its class.
LOE Approaching
Product is in late lifecycle decline with minimal commercial momentum; teams are likely small and focused on patient retention rather than expansion.
Mechanism of Action
gram-negative coccobacillus. Most strains of H. influenzae that cause invasive disease (e.g., sepsis and meningitis) are H. influenzae type b. The response to ActHIB vaccine is typical of a T-dependent immune response to antigens. The prominent isotype of anti-capsular PRP antibody induced by…
Indications (2)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.