NDATOPICALOINTMENT
Approved
Dec 1982
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
3/8 — Basic
ACLOVATE (alclometasone dipropionate) by Sandoz is clinical pharmacology like other topical corticosteroids, alclometasone dipropionate has anti-inflammatory, antipruritic, and vasoconstrictive properties. First approved in 1982.
Drug data last refreshed Yesterday
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ACLOVATE (alclometasone dipropionate) is a low-to-medium potency topical corticosteroid ointment approved in 1982 for inflammatory skin conditions. It treats eczema, psoriasis, pruritus, and allergic dermatitis by inducing lipocortin proteins that inhibit prostaglandin and leukotriene synthesis, reducing inflammation and itching. Approximately 3% systemic absorption occurs with intact skin contact, making it suitable for localized dermatological use.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30/100) signals defensive positioning and potential consolidation within Sandoz's dermatology portfolio.
Mechanism of Action
CLINICAL PHARMACOLOGY Like other topical corticosteroids, alclometasone dipropionate has anti-inflammatory, antipruritic, and vasoconstrictive properties. The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear. However, corticosteroids are thought to act by…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.