ACITRETIN

Post-LOE

acitretin

ANDAORALCAPSULE
Approved
Apr 2013
Lifecycle
Post-LOE
Competitive Pressure
30/100
Clinical Trials
5

Mechanism of Action

CLINICAL PHARMACOLOGY The mechanism of action of acitretin is unknown. Pharmacokinetics Absorption Oral absorption of acitretin is optimal when given with food. For this reason, acitretin was given with food in all of the following trials. After administration of a single 50-mg oral dose of…

Pharmacologic Class:

Retinoid

Clinical Trials (5)

NCT01228409Phase 4Unknown

Low-Dose (17.5 mg/Day) Acitretin: Comparable Efficacy Without the Side Effects?

Started Oct 2010
20 enrolled
Psoriasis
NCT00936065Phase 4Completed

Study Evaluating the Efficacy and Safety of Etanercept and Acitretin in Korean Patient With Moderate to Severe Psoriasis

Started Jul 2009
60 enrolled
Moderate to Severe Psoriasis
NCT00707070Phase 4Unknown

Combining Acitretin and Efalizumab in the Therapy of Chronic Plaque Psoriasis

Started Sep 2008
100 enrolled
Chronic Plaque Psoriasis
NCT00003611N/ACompleted

Acitretin in Preventing Skin Cancers in Patients With Previously Treated Skin Cancers Who Have Undergone Organ Transplantation

Started May 2000
129 enrolled
Non-melanomatous Skin Cancer
NCT00002143Phase 3Completed

Treatment of Psoriasis Using Acitretin in HIV-Positive Patients

30 enrolled
HIV InfectionsPsoriasis