NDAORALCAPSULE
Approved
Oct 1957
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
ACHROMYCIN V (tetracycline hydrochloride) by Pfizer is clinical pharmacology tetracyclines are readily absorbed and are bound to plasma protein in varying degrees. First approved in 1957.
Drug data last refreshed 7h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ACHROMYCIN V (tetracycline hydrochloride) is a broad-spectrum bacteriostatic antibiotic approved in 1957 that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. It is active against gram-positive and gram-negative bacteria, rickettsiae, chlamydia, and certain parasites, making it useful for infections ranging from respiratory to sexually transmitted diseases. The drug is administered orally as a capsule and remains a foundational antibiotic despite its age.
LOE Approaching
As a legacy product approaching loss of exclusivity with moderate competitive pressure (30%), the brand team is likely small and focused on defensive positioning and cost management rather than growth initiatives.
Mechanism of Action
CLINICAL PHARMACOLOGY Tetracyclines are readily absorbed and are bound to plasma protein in varying degrees. They are concentrated by the liver in the bile and excreted in the urine and feces at high concentrations in a biologically active form. Microbiology Tetracyclines are primarily…
Indications
Worked on ACHROMYCIN V at Pfizer? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.