NDAINJECTIONINJECTABLE
Approved
Jul 1954
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
ACHROMYCIN (procaine hydrochloride; tetracycline hydrochloride) by Pfizer is clinical pharmacology novocain stabilizes the neuronal membrane and prevents the initiation and transmission of nerve impulses, thereby effecting local anesthesia. First approved in 1954.
Drug data last refreshed 17h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ACHROMYCIN is a combination injectable local anesthetic containing procaine hydrochloride and tetracycline hydrochloride, approved by Pfizer in 1954. Procaine stabilizes neuronal membranes to effect local anesthesia with rapid onset (2-5 minutes) and short duration (1-1.5 hours), while the tetracycline component provides antimicrobial activity. The drug is administered via injection for localized pain control and infection prevention in surgical and dental procedures.
LOE Approaching
With LOE approaching and moderate competitive pressure (30), this mature product faces declining commercial support; career growth opportunities are limited unless involved in cost-optimization or supply-chain roles.
Mechanism of Action
CLINICAL PHARMACOLOGY NOVOCAIN stabilizes the neuronal membrane and prevents the initiation and transmission of nerve impulses, thereby effecting local anesthesia. NOVOCAIN lacks surface anesthetic activity. The onset of action is rapid (2 to 5 minutes) and the duration of action is relatively…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
ACHROMYCIN offers limited career growth due to its LOE-approaching status and zero linked job openings. Roles on this product typically focus on cost management, compliance, and supply-chain efficiency rather than commercial expansion or innovation.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.