NDAINJECTIONINJECTABLE
Approved
Jul 1954
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
ACHROMYCIN (procaine hydrochloride; tetracycline hydrochloride) by Pfizer is clinical pharmacology novocain stabilizes the neuronal membrane and prevents the initiation and transmission of nerve impulses, thereby effecting local anesthesia. First approved in 1954.
Drug data last refreshed 19h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ACHROMYCIN is a fixed combination of procaine hydrochloride (local anesthetic) and tetracycline hydrochloride (broad-spectrum antibiotic) administered by injection. It stabilizes neuronal membranes to block nerve impulses for local anesthesia while providing systemic antibiotic coverage. The product has been in use since 1954 and is approaching loss of exclusivity.
LOE Approaching
As a legacy product approaching loss of exclusivity with moderate competitive pressure (30%), this brand faces declining team resources and is likely in defensive maintenance mode rather than growth.
Mechanism of Action
CLINICAL PHARMACOLOGY NOVOCAIN stabilizes the neuronal membrane and prevents the initiation and transmission of nerve impulses, thereby effecting local anesthesia. NOVOCAIN lacks surface anesthetic activity. The onset of action is rapid (2 to 5 minutes) and the duration of action is relatively…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on ACHROMYCIN offers limited career advancement due to zero linked job openings and its LOE-approaching lifecycle. This role is best suited for professionals seeking stability in a legacy franchise or defensive portfolio management experience rather than growth-oriented careers.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.