ACETAMINOPHEN AND CODEINE PHOSPHATE

Post-LOE

acetaminophen; codeine phosphate

ANDAORALTABLET
Approved
Jan 1980
Lifecycle
Post-LOE
Competitive Pressure
30/100

Mechanism of Action

CLINICAL PHARMACOLOGY Mechanism of Action Codeine is an opioid agonist relatively selective for the mu-opioid receptor, but with a much weaker affinity than morphine. The analgesic properties of codeine have been speculated to come from its conversion to morphine, although the exact mechanism of…