ACCUPRIL

LOE Approaching

quinapril hydrochloride

R-Pharm US
NDAORALTABLET
Approved
Nov 1991
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1

Mechanism of Action

CLINICAL PHARMACOLOGY Mechanism of Action Quinapril is deesterified to the principal metabolite, quinaprilat, which is an inhibitor of ACE activity in human subjects and animals. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor, angiotensin II. The…

Indications (4)

hypertensionto lower blood pressurethe management of heart failureheart failure

Clinical Trials (1)

NCT00269243Phase 4Completed

Management With Accupril Post Bypass Graft

Started Nov 1999
CABG
Company
R-Pharm US
R-Pharm US
NJ - Princeton
External Resources
DailyMed
Full prescribing information
FDA Drugs@FDA
FDA approval history
RxNorm
Drug nomenclature & identifiers