NDAORALTABLET
Approved
Sep 1996
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
2
Data completeness
5/8 — Partial
ACCOLATE (zafirlukast) by PharmaIN is leukotriene receptor antagonists [moa]. First approved in 1996.
Drug data last refreshed 10h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ACCOLATE (zafirlukast) is an oral leukotriene receptor antagonist approved in 1996 for asthma management. It works by blocking leukotriene receptors in the airways, reducing inflammation and bronchoconstriction. This small-molecule therapy is typically used as a maintenance or adjunctive treatment for persistent asthma.
$0.008BPart D
LOE ApproachingDeclining
Minimal commercial activity with only 21 Medicare claims annually signals a mature product with shrinking market presence and reduced team investment.
Mechanism of Action
Leukotriene Receptor Antagonists
Pharmacologic Class:
Leukotriene Receptor Antagonist
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (2)
Crossover Study of Zafirlukast in Preventing Allergen-induced Signs and Symptoms in Response to Cat Dander Challenge
Started Dec 2025
12 enrolled
Allergy to Cats
Bioequivalence Study of Zafirlukast Tablets 20 mg of Dr. Reddy's Laboratories Limited Under Fasting Condition
Started Dec 2007
44 enrolled
Healthy
Career Relevance
Working on ACCOLATE offers limited career growth opportunity given zero linked job postings, minimal commercial spending ($8K Part D), and LOE-approaching lifecycle status. Roles on this team typically focus on market maintenance, managed-care negotiations, and defending market share against generics rather than innovation or expansion.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.