ABILIFY

LOE ApproachingSM

aripiprazole

NDAINTRAMUSCULARINJECTABLE
Approved
Sep 2006
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

unknown. The efficacy of aripiprazole could be mediated through a combination of partial agonist activity at dopamine D 2 and serotonin 5-HT 1A receptors and antagonist activity at 5-HT 2A receptors.

Clinical Trials (5)

NCT04907279N/AUnknown

Aripiprazole Once-Monthly in Hospitalized Patients (INITIATE)

Started Nov 2021
200 enrolled
SchizophreniaSchizo Affective DisorderBipolar I Disorder
NCT04812379N/ACompleted

Specified Drug-use Survey on Abilify Prolonged Release Aqueous Suspension for IM Injection (Prevention of Relapse of Mood Episodes in BP)

Started Apr 2021
535 enrolled
Bipolar Disorder I
NCT04203056Phase 4Terminated

Aripiprazole Lauroxil for Preventing Psychotic Relapse After an Initial Schizophrenia Episode

Started Dec 2019
NCT04030143Phase 1/2Completed

A Trial of Multiple-doses of Aripiprazole in Adults With Schizophrenia or Bipolar 1 Disorder

Started Aug 2019
266 enrolled
SchizophreniaBipolar I Disorder
NCT03892889Phase 3Terminated

A Trial in Adult Participants With Schizophrenia Treated Prospectively for 6-months With Abilify MyCite®

Started Apr 2019
277 enrolled
Schizophrenia