VP, DMD Commercial Asset Lead

Dyne Therapeutics·
Waltham, MA
2w ago
Senior3000GL - CCONeurology
From $272K/yr(estimated)

Description

<div class="content-intro"><h3>Company Overview:</h3> <p>Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at <a href="https://www.dyne-tx.com/">https://www.dyne-tx.com/</a>, and follow us on <a href="https://x.com/dyne_tx">X</a>, <a href="https://www.linkedin.com/company/dynetx/">LinkedIn</a> and <a href="https://www.facebook.com/DyneTherapeutic/">Facebook</a>.</p></div><p><strong>Role Summary:</strong></p> <p data-ccp-border-bottom="0px none #000000" data-ccp-padding-bottom="0px" data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"><span data-contrast="auto"><span data-ccp-parastyle="Body" data-ccp-parastyle-defn="{"ObjectId":"b669530d-9cee-5fd4-8da3-4cdbed7bfaa2|1","ClassId":1073872969,"Properties":[469775450,"Body",201340122,"2",134233614,"true",469778129,"Body",335572020,"1",469777841,"Helvetica",469777842,"Helvetica",469777843,"Helvetica",469777844,"Helvetica",469769226,"Helvetica",335551500,"0",268442635,"22"]}">The </span><span data-ccp-parastyle="Body">VP, </span><span data-ccp-parastyle="Body">DMD </span><span data-ccp-parastyle="Body">Commercial Asset</span><span data-ccp-parastyle="Body"> </span><span data-ccp-parastyle="Body">Lead</span><span data-ccp-parastyle="Body"> </span><span data-ccp-parastyle="Body">(CAL) </span><span data-ccp-parastyle="Body">is a passionate </span><span data-ccp-parastyle="Body">driver for </span><span data-ccp-parastyle="Body">maximizing the value </span><span data-ccp-parastyle="Body">of </span><span data-ccp-parastyle="Body">Dyne’s DMD </span><span data-ccp-parastyle="Body">commercial </span><span data-ccp-parastyle="Body">asset</span><span data-ccp-parastyle="Body">s</span><span data-ccp-parastyle="Body"> </span><span data-ccp-parastyle="Body">with a global perspective, who brings adaptable leadership</span><span data-ccp-parastyle="Body"> to</span><span data-ccp-parastyle="Body"> </span></span><span data-contrast="none"><span data-ccp-parastyle="Body">d</span><span data-ccp-parastyle="Body">evelop and implement commercial</span><span data-ccp-parastyle="Body">ization</span><span data-ccp-parastyle="Body"> strategies to maximize the </span><span data-ccp-parastyle="Body">reach and </span><span data-ccp-parastyle="Body">value </span><span data-ccp-parastyle="Body">creation </span><span data-ccp-parastyle="Body">of </span><span data-ccp-parastyle="Body">Dyne’s DMD</span><span data-ccp-parastyle="Body"> </span><span data-ccp-parastyle="Body">commercial</span><span data-ccp-parastyle="Body"> </span><span data-ccp-parastyle="Body">assets</span><span data-ccp-parastyle="Body"> in the </span><span data-ccp-parastyle="Body">neuro muscular</span><span data-ccp-parastyle="Body"> portfolio. </span></span><span data-ccp-props="{"335559739":120}"> </span></p> <p data-ccp-border-bottom="0px none #000000" data-ccp-padding-bottom="0px" data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"><span data-contrast="none"><span data-ccp-parastyle="Body">This</span><span data-ccp-parastyle="Body"> mandate</span><span data-ccp-parastyle="Body"> includes market analysis, competitive positioning, </span><span data-ccp-parastyle="Body">launch readiness and </span><span data-ccp-parastyle="Body">execution</span><span data-ccp-parastyle="Body"> and input into lifecycle </span><span data-ccp-parastyle="Body">management</span></span><span data-contrast="auto"><span data-ccp-parastyle="Body"> in the </span><span data-ccp-parastyle="Body">relentless pursuit of long-term success </span><span data-ccp-parastyle="Body">in bringing the asset to </span><span data-ccp-parastyle="Body">patients </span><span data-ccp-parastyle="Body">globally.</span><span data-ccp-parastyle="Body"> The </span><span data-ccp-parastyle="Body">C</span><span data-ccp-parastyle="Body">AL</span><span data-ccp-parastyle="Body"> is a highly visible leadership role. </span><span data-ccp-parastyle="Body">As a key member of</span><span data-ccp-parastyle="Body"> an </span><span data-ccp-parastyle="Body">experienced</span><span data-ccp-parastyle="Body"> Program </span><span data-ccp-parastyle="Body">Team</span><span data-ccp-parastyle="Body">,</span><span data-ccp-parastyle="Body"> </span><span data-ccp-parastyle="Body">the</span><span data-ccp-parastyle="Body"> </span><span data-ccp-parastyle="Body">C</span><span data-ccp-parastyle="Body">AL </span><span data-ccp-parastyle="Body">will </span><span data-ccp-parastyle="Body">work with the</span><span data-ccp-parastyle="Body"> cross-functional team </span><span data-ccp-parastyle="Body">to</span><span data-ccp-parastyle="Body"> influence</span><span data-ccp-parastyle="Body"> and shape</span><span data-ccp-parastyle="Body"> the Program strategy</span><span data-ccp-parastyle="Body">. The </span><span data-ccp-parastyle="Body">C</span><span data-ccp-parastyle="Body">AL leads all efforts in</span><span data-ccp-parastyle="Body"> </span><span data-ccp-parastyle="Body">defining the commercialization strategy, strategic imperatives</span><span data-ccp-parastyle="Body">, critical success factors,</span><span data-ccp-parastyle="Body"> executional</span><span data-ccp-parastyle="Body"> priorities, </span><span data-ccp-parastyle="Body">and launch efforts</span><span data-ccp-parastyle="Body"> </span><span data-ccp-parastyle="Body">together with the launch teams of the affiliates, </span><span data-ccp-parastyle="Body">bringing both a 'future-orientation' toward the </span><span data-ccp-parastyle="Body">goal</span><span data-ccp-parastyle="Body"> of broad, global access for patients in need, and a "pragmatic-orientation" to chart the path, mitigate risks, cultivate options</span><span data-ccp-parastyle="Body">. </span><span data-ccp-parastyle="Body">The </span><span data-ccp-parastyle="Body">C</span><span data-ccp-parastyle="Body">AL </span><span data-ccp-parastyle="Body">collaborate</span><span data-ccp-parastyle="Body">s</span><span data-ccp-parastyle="Body"> with</span><span data-ccp-parastyle="Body"> program team</span><span data-ccp-parastyle="Body">,</span><span data-ccp-parastyle="Body"> </span><span data-ccp-parastyle="Body">functional </span><span data-ccp-parastyle="Body">leads</span><span data-ccp-parastyle="Body"> </span><span data-ccp-parastyle="Body">and affiliate teams</span><span data-ccp-parastyle="Body"> </span><span data-ccp-parastyle="Body">to achieve a </span><span data-ccp-parastyle="Body">differentiated product profile, competitive label, </span><span data-ccp-parastyle="Body">broad </span><span data-ccp-parastyle="Body">reimbursement</span><span data-ccp-parastyle="Body"> and </span><span data-ccp-parastyle="Body">highly successful</span><span data-ccp-parastyle="Body"> launch</span><span data-ccp-parastyle="Body">es</span><span data-ccp-parastyle="Body"> globally</span><span data-ccp-parastyle="Body"> starting with the US launch</span><span data-ccp-parastyle="Body">.</span></span><span data-contrast="none"><span data-ccp-parastyle="Body"> </span></span><span data-ccp-props="{"335559739":120}"> </span></p> <p data-ccp-border-bottom="0px none #000000" data-ccp-padding-bottom="0px" data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"><span data-contrast="none"><span data-ccp-parastyle="Body">The </span><span data-ccp-parastyle="Body">C</span><span data-ccp-parastyle="Body">AL, as </span><span data-ccp-parastyle="Body">a </span><span data-ccp-parastyle="Body">member of the program team, </span><span data-ccp-parastyle="Body">is </span><span data-ccp-parastyle="Body">responsible </span><span data-ccp-parastyle="Body">for</span><span data-ccp-parastyle="Body"> securing</span><span data-ccp-parastyle="Body"> commercialization</span><span data-ccp-parastyle="Body"> and</span><span data-ccp-parastyle="Body"> works hand in hand </span><span data-ccp-parastyle="Body">in strong</span><span data-ccp-parastyle="Body"> partne</span><span data-ccp-parastyle="Body">rship</span><span data-ccp-parastyle="Body"> with </span><span data-ccp-parastyle="Body">the Program Lead, </span><span data-ccp-parastyle="Body">the </span><span data-ccp-parastyle="Body">Head of Commercialization</span><span data-ccp-parastyle="Body">, all functional </span><span data-ccp-parastyle="Body">leaders</span><span data-ccp-parastyle="Body"> and the </span><span data-ccp-parastyle="Body">affiliate launch teams</span><span data-ccp-parastyle="Body">.</span></span><span data-ccp-props="{"335559739":120}"> </span></p> <p data-ccp-border-bottom="0px none #000000" data-ccp-padding-bottom="0px" data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"><span data-contrast="auto"><span data-ccp-parastyle="Body">This role is</span><span data-ccp-parastyle="Body"> based</span><span data-ccp-parastyle="Body"> </span><span data-ccp-parastyle="Body">onsite</span><span data-ccp-parastyle="Body"> in Waltham, MA</span><span data-ccp-parastyle="Body">.</span><span data-ccp-parastyle="Body"> </span></span><span data-ccp-props="{"335559739":120}"> </span></p> <p data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"> <br><strong><span data-contrast="none"><span data-ccp-parastyle="Body">Primary Responsibilities</span><span data-ccp-parastyle="Body"> Include</span><span data-ccp-parastyle="Body">:</span></span></strong><span data-ccp-props="{"335559739":120}"> </span></p> <ul> <li><span data-contrast="auto">Define global asset commercialization strategy and plan to achieve milestones and timelines for successful launches</span><span data-ccp-props="{"335559739":160,"469777462":[0,720],"469777927":[0,0],"469777928":[1,1]}"> </span></li> <li><span data-contrast="auto">As a key member of the Program Team and Head of DMD Commercial Sub Team, they ensure that all key pillars for successful commercialization for the assets are secured – starting with differentiation in endpoints to achieve a competitive product profile/label, regulatory strategy, filing strategy, with value & access to secure the value proposition for the assets and achieve reimbursement in US and at the right time globally, partner with supply, medical, marketing, digital and the data team to prepare successful launch strategy and execution for all key markets starting with US. </span><span data-ccp-props="{"335559739":160,"469777462":[0,720],"469777927":[0,0],"469777928":[1,1]}"> </span></li> <li><span data-contrast="auto">Provide input and expertise to a robust and well-understood program strategy with the key objective of gaining the approvals of potentially life-changing medicines for patients around the world to generate value for patients and shareholders and maximize topline growth.</span><span data-ccp-props="{"335559739":160,"469777462":[0,720],"469777927":[0,0],"469777928":[1,1]}"> </span></li> <li><span data-contrast="auto">Structure and facilitate critical cross-functional decisions on commercialization aspects of the asset within Program Teams and senior leadership teams, bringing all relevant perspectives to bear while driving to efficient decisions in a fast-paced environment.</span><span data-ccp-props="{"335559739":160,"469777462":[0,720],"469777927":[0,0],"469777928":[1,1]}"> </span></li> <li><span data-contrast="auto">Working with cross-functional launch team in key markets, starting with the US team, and Strategic Commercialization Partners to secure reimbursement and successful launches, by propelling successful launch execution from one country to the other. </span><span data-ccp-props="{"335559739":160,"469777462":[0,720],"469777927":[0,0],"469777928":[1,1]}"> </span></li> <li><span data-contrast="auto">In close collaboration with the Program Lead and Head of Commercialization, consider and advocate for the needs of the commercial asset in the context of Dyne’s corporate strategy and priorities. </span><span data-ccp-props="{"335559739":160,"469777462":[0,720],"469777927":[0,0],"469777928":[1,1]}"> </span></li> <li><span data-contrast="auto">Drive preparation and presentation of materials for Board of Directors on asset commercialization topics</span><span data-ccp-props="{"335559739":160,"469777462":[0,720],"469777927":[0,0],"469777928":[1,1]}"> </span></li> <li><span data-contrast="auto">Maintain clear, open, and proactive communication with the senior leadership team and other stakeholders regarding commercialization strategy, status, priorities, risks and needs, and facilitate appropriate decision-making.</span><span data-ccp-props="{"335559739":160,"469777462":[0,720],"469777927":[0,0],"469777928":[1,1]}"> </span></li> <li><span data-contrast="auto">Keep abreast of competitor landscape and development in the fields of muscle diseases and oligonucleotide drug discovery and development.</span><span data-ccp-props="{"335559739":160,"469777462":[0,720],"469777927":[0,0],"469777928":[1,1]}"> </span></li> <li><span data-contrast="auto">Build visible, constructive, and credible presence within the DMD community including with KOLs, the holistic teams engaged in patient care and patient community. </span><span data-ccp-props="{"335559739":160,"469777462":[0,720],"469777927":[0,0],"469777928":[1,1]}"> </span></li> <li><span data-contrast="auto">Participate in business development activities, as needed, including opportunity evaluations and due diligence.</span><span data-ccp-props="{"335559739":160,"469777462":[0,720],"469777927":[0,0],"469777928":[1,1]}"> </span></li> <li><span data-contrast="auto">Provide a motivating leadership example within Dyne more broadly during periods of rapid growth.</span><span data-ccp-props="{"335559739":160,"469777462":[0,720],"469777927":[0,0],"469777928":[1,1]}"> </span></li> <li><span data-contrast="auto">Foster a culture of collaboration, innovation, discovery, and cutting-edge research.</span><span data-ccp-props="{"335559739":160,"469777462":[0,720],"469777927":[0,0],"469777928":[1,1]}"> </span></li> <li><span data-contrast="auto">Focused on scientific excellence, open communication, and continuous improvement.</span><span data-ccp-props="{"335559739":160,"469777462":[0,720],"469777927":[0,0],"469777928":[1,1]}"> </span></li> <li><span data-contrast="auto">Role model Dyne’s core values. </span><span data-ccp-props="{"335559739":160,"469777462":[0,720],"469777927":[0,0],"469777928":[1,1]}"> </span></li> </ul> <p data-ccp-border-bottom="0px none #000000" data-ccp-padding-bottom="0px" data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"><span data-ccp-props="{}"> </span></p> <p data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"><strong><span data-contrast="none"><span data-ccp-parastyle="Body">Education and Skills Requirements:</span></span></strong><span data-ccp-props="{"335559739":120}"> </span></p> <ul> <li><span data-contrast="auto">Bachelor’s degree in a relevant scientific, medical, or business discipline required; advanced degree (MD, PhD, PharmD, MBA, or Master’s in Life Sciences) strongly preferred.</span><span data-ccp-props="{"335557856":16777215}"> </span></li> <li><span data-contrast="auto">Minimum of 20 years of experience in the biopharmaceutical industry.</span><span data-ccp-props="{"335557856":16777215}"> </span></li> <li><span data-contrast="auto">15+ years of commercialization and cross-functional leadership experience within the biopharmaceutical industry, including substantial involvement in clinical development strategy, regulatory interactions, filing preparation, and lifecycle planning.</span><span data-ccp-props="{"335557856":16777215}"> </span></li> <li><span data-contrast="auto">Extensive experience leading global product launches, including development of launch strategy, execution, and cross-functional commercialization planning.</span><span data-ccp-props="{"335557856":16777215}"> </span></li> <li><span data-contrast="auto">Rare disease launch experience strongly preferred; neuromuscular disease experience highly advantageous.</span><span data-ccp-props="{"335557856":16777215}"> </span></li> <li><em><span data-contrast="auto">Proven track record of:</span></em><span data-ccp-props="{"335557856":16777215}"> </span> <ul> <li><span data-contrast="auto">Delivering on business objectives in fast--paced, highstakes environments.</span><span data-ccp-props="{"335557856":16777215}"> </span></li> <li><span data-contrast="auto">Steering assets from late stage development through approval and launch.</span><span data-ccp-props="{"335557856":16777215}"> </span></li> <li><span data-contrast="auto">Influencing global and U.S. market access, value evidence generation, and reimbursement readiness.</span><span data-ccp-props="{"335557856":16777215}"> </span></li> </ul> </li> <li><span data-contrast="auto">Experience collaborating closely with clinical development, medical affairs, supply chain, marketing, digital/data teams, and affiliate launch organizations.</span><span data-ccp-props="{"335557856":16777215,"335559685":720}"> </span></li> <li><span data-contrast="auto">Expertise in global asset commercialization, including competitive positioning, launch sequencing, market shaping, and lifecycle strategy.</span><span data-ccp-props="{"335557856":16777215,"335559685":720}"> </span></li> <li><span data-contrast="auto">Ability to synthesize scientific, clinical, regulatory, and market data to guide asset and commercialization strategy.</span><span data-ccp-props="{"335557856":16777215,"335559685":720}"> </span></li> <li><span data-contrast="auto">Fluency with digital launch tools, analytics platforms, and data driven decision-making.</span><span data-ccp-props="{"335557856":16777215,"335559685":720}"> </span></li> <li><span data-contrast="auto">Entrepreneurial, self-driven leader capable of articulating a compelling vision and mobilizing high performing cross functional teams.</span><span data-ccp-props="{"335557856":16777215,"335559685":720}"> </span></li> <li><span data-contrast="auto">Strong people leadership skills with the ability to coach, influence, and inspire diverse functional experts.</span><span data-ccp-props="{"335557856":16777215,"335559685":720}"> </span></li> <li><span data-contrast="auto">Exceptional communication skills, including clear and effective engagement with executive leadership, affiliates, external partners, Boards of Directors, and patient communities.</span><span data-ccp-props="{"335557856":16777215,"335559685":720}"> </span></li> <li><span data-contrast="auto">Proven ability to build strong, credible relationships with KOLs, advocacy groups, payers, regulators, and other key stakeholders.</span><span data-ccp-props="{"335557856":16777215,"335559685":720}"> </span></li> <li><span data-contrast="auto">Comfortable leading through ambiguity, adapting to evolving priorities, and driving alignment in a dynamic environment.</span><span data-ccp-props="{"335557856":16777215,"335559685":720}"> </span></li> <li><span data-contrast="auto">High integrity, strong patient centric mindset, and alignment with Dyne’s core values.</span><span data-ccp-props="{"335557856":16777215,"335559685":720}"> </span></li> <li><span data-contrast="auto">Strong sense of urgency with the ability to pace and prioritize workstreams in competitive and fast-moving environments.</span><span data-ccp-props="{"335557856":16777215,"335559685":720}"> </span></li> <li><span data-contrast="auto">Transparent, inclusive communicator with a collaborative leadership style.</span><span data-ccp-props="{"335557856":16777215,"335559685":720}"> </span></li> </ul><div class="content-pay-transparency"><div class="pay-input"><div class="title">MA Pay Range</div><div class="pay-range"><span>$272,000</span><span class="divider">—</span><span>$340,000 USD</span></div></div></div><div class="content-conclusion"><p> </p> <p>The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills.</p> <p>The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements.  Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.</p> <p class="Body"><em><span style="font-family: 'Arial',sans-serif; color: #626262;">Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.</span></em></p></div>
Dyne Therapeutics

Dyne Therapeutics

BIOTECHNOLOGY

Antibody-Oligonucleotide Treatments for Muscle Diseases

LocationWALTHAM, MA
Employees201-500
Open Jobs50
NeurologyRare Diseases
View Company Profile

Pipeline

Motor Outcomes to Validate Evaluations in FSHD (MOVE FSHD)N/A
FSHD-specific functional rating scaleN/A
DYNE-251Phase 1/2
DYNE-101Phase 1/2